Aspiration-Induced Acute Lung Injury: Experimental Morphological Study
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چکیده
منابع مشابه
Glutamine Attenuates Acute Lung Injury Caused by Acid Aspiration
Inadequate ventilator settings may cause overwhelming inflammatory responses associated with ventilator-induced lung injury (VILI) in patients with acute respiratory distress syndrome (ARDS). Here, we examined potential benefits of glutamine (GLN) on a two-hit model for VILI after acid aspiration-induced lung injury in rats. Rats were intratracheally challenged with hydrochloric acid as a first...
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Although many various models have been improved in order to form human features of Acute Respiratory Distress Syndrome (ARDS) in animals, there is no single animal model that satisfactorily exhibits all of the histopathological components of human ARDS. Therefore, when choosing an ARDS animal model, it is important to consider the ARDS key property to be tested as a study hypothesis and choose ...
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Aim: Seawater drowning induced-acute lung injury (ALI) is a serious clinical condition characterized by refractory hypoxemia, enhanced alveolar-capillary permeability, hemorrhage, and uncontrolled overwhelming inflammatory responses. Hydrogen sulfide (H2S) is an endogenous gaseous mediator that plays an important role in the physiological and pathophysiological conditions, especially in some in...
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Acute lung injury (ALI) in combination with acute kidney injury carries a mortality approaching 80% in the intensive care unit. Recently, attention has focused on the interaction of the lung and kidney in the setting of ALI and mechanical ventilation (MV). Small animal models of ALI and MV have demonstrated changes in inflammatory mediators, water channels, apoptosis, and function in the kidney...
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Objective(s):Therapies with high levels of oxygen are commonly used in the management of critical care. However, prolonged exposure to hyperoxia can cause acute lung injury. Although oxidative stress and inflammation are purported to play an important role in the pathogenesis of acute lung injury, the exact mechanisms are still less known in the hyperoxic acute lung injury (HALI). Materials ...
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ژورنال
عنوان ژورنال: General Reanimatology
سال: 2008
ISSN: 2411-7110,1813-9779
DOI: 10.15360/1813-9779-2008-3-5